The Liver

The Liver

The liver is the largest organ of the body, weighing about 1.5 kg, and is located in the upper right part of the abdomen. It has very important functions such as storage and secretion of food; synthesis of glucose, fatty acids, and protein; production and secretion of bile; and elimination of toxins. The liver is the primary organ responsible for carrying out crucial functions such as the digestion of carbohydrates, proteins, and fats, the detoxification of drugs and poisons, the synthesis of vitamins and bile, and the production of components required for blood coagulation. Its absence is life-threatening, but thanks to its unique capacity to regenerate itself, even if 75% of it is removed (this may vary in different cases), the liver can grow and resume normal function in a short time.

 

Malignant tumors can be found in the liver, as well as non-malignant lesions such as cysts (often hydatid cysts), hemangiomas, focal nodular hyperplasia, adenomas, hamartomas, abscesses, and hemangiomas. Liver cancer, gallbladder cancer, and biliary tract cancer are primary tumors of the liver. However, a significant proportion of liver tumors consists of metastatic tumors from other organs. The most common origins of metastatic tumors are the colon and the rectum. Cancers developing in many other organs also metastasize to the liver. 

The excision of the tumor lobe or segment is the primary treatment for liver tumors (resection). This is also the case for a significant proportion of metastases. It is now possible to resect several metastatic cancers for which surgery was not previously considered. The key considerations in resection are whether it is technically feasible to remove the tumor and whether the remaining liver is sufficient for the patient. A meticulous, detailed multidisciplinary examination and experience are especially important in making this decision. In cases where the remaining liver is not enough, there are also techniques to enlarge the remaining liver. The application of these techniques also requires skill and experience. 

The liver has complicated anatomy. It is one of the most blood-rich organs of the body. Liver diseases are usually complicated diseases. This situation also causes liver surgery to be complicated. Complications during and following surgery are possible, particularly bleeding. With rigorous preoperative planning, a skilled surgical team, appropriate surgical technique, and excellent postoperative care, these complications can be minimized.

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